4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester
Propargyl-PEG5-NHS ester
CAS: 1393330-40-9
Molecular Formula: C18H27NO9
4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester - Names and Identifiers
4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester - Physico-chemical Properties
| Molecular Formula | C18H27NO9 |
| Molar Mass | 401.41 |
| Density | 1.23±0.1 g/cm3(Predicted) |
| Boling Point | 497.6±55.0 °C(Predicted) |
| Storage Condition | 2-8℃ |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester - Reference Information
| biological activity | Propargyl-PEG5-NHS ester is a PROTAC connection bridge, belonging to PEG class and Alkyl/ether class. Propargyl-PEG5-NHS ester can be used to synthesize a series of PROTAC molecules. Propargyl-PEG5-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs). |
| target | Cleavable PEGs Alkyl/ether |
| in vitro research | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 15:16:37
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View History
4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-[[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]methyl]-
Spirostan, 3,3-dimethoxy-, (5α,20β,25R)- (9CI)
287730-69-2
701939-09-5
1-(4-pyridyl)pyrazole-4-boronic Acid
9-(Methylthio)bipyrromethene Difluoroborate
九里香内酯
Ethinazone Hydrochloride
六氢对二甲苯
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-[[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]methyl]-
Spirostan, 3,3-dimethoxy-, (5α,20β,25R)- (9CI)
287730-69-2
701939-09-5
1-(4-pyridyl)pyrazole-4-boronic Acid
9-(Methylthio)bipyrromethene Difluoroborate
九里香内酯
Ethinazone Hydrochloride
六氢对二甲苯